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Journal Article 4

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2022 1

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carbohydrate 2

bioimaging 1

biological macromolecules 1

cancer diagnosis and treatment 1

cholangiocarcinoma 1

continuous glucose monitoring 1

exopolysaccharide 1

glyco-functionalised QD 1

leptin 1

low-carbohydrate diet 1

mean sensor glucose 1

nonalcoholic fatty liver disease 1

obesity 1

prognostic factors 1

regenerative medicine 1

serum carbohydrate antigen 19-9 1

tissue engineering 1

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Low-carbohydrate diets lead to greater weight loss and better glucose homeostasis than exercise: a randomized

Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 460-471 doi: 10.1007/s11684-021-0861-6

Abstract: This study enrolled adults with overweight or obesity to explore whether either low-carbohydrate dietThe subjects either adopted LCD (carbohydrate intake<50 g/day) or performed moderate-to-vigorous exercise

Keywords： low-carbohydrate diet obesity nonalcoholic fatty liver disease continuous glucose monitoring mean

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Serum carbohydrate antigen (CA) 19-9 as a prognostic factor in cholangiocarcinoma: A meta-analysis

Shang-Long LIU, Zi-Fang SONG, Qing-Gang HU, Shao-Bo HU, Jun LI, Qi-Chang ZHENG, Duo SHAN,

Frontiers of Medicine 2010, Volume 4, Issue 4, Pages 457-462 doi: 10.1007/s11684-010-0240-1

Abstract: This study was performed to determine the prognostic role of preoperative serum carbohydrate antigen

Keywords： cholangiocarcinoma prognostic factors serum carbohydrate antigen 19-9

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Microorganism-derived biological macromolecules for tissue engineering

Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 358-377 doi: 10.1007/s11684-021-0903-0

Abstract: According to literature, certain microorganism productions mediate biological effects. However, their beneficial characteristics remain unclear. Nowadays, scientists concentrate on obtaining natural materials from live creatures as new sources to produce innovative smart biomaterials for increasing tissue reconstruction in tissue engineering and regenerative medicine. The present review aims to introduce microorganism-derived biological macromolecules, such as pullulan, alginate, dextran, curdlan, and hyaluronic acid, and their available sources for tissue engineering. Growing evidence indicates that these materials can be used as biological material in scaffolds to enhance regeneration in damaged tissues and contribute to cosmetic and dermatological applications. These natural-based materials are attractive in pharmaceutical, regenerative medicine, and biomedical applications. This study provides a detailed overview of natural-based biomaterials, their chemical and physical properties, and new directions for future research and therapeutic applications.

Keywords： biological macromolecules regenerative medicine tissue engineering exopolysaccharide carbohydrate

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Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

Jayshree Ashree, Qi Wang, Yimin Chao

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 3, Pages 365-377 doi: 10.1007/s11705-019-1863-7

Abstract: Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.

Keywords： carbohydrate leptin glyco-functionalised QD bioimaging cancer diagnosis and treatment